Guoyin Shen's research covers a broad range of subjects aimed at understanding the behavior of materials under high-pressure and extreme temperature conditions. The research activities include investigation of phase transformations and melting lines in molecular solids, oxides and metals; characterization of liquids and amorphous materials under high-pressure/temperature conditions; measurement of crystal chemistry, elastic and transportation properties of deep Earth materials at pressure-temperature conditions equivalent to the Earth’s interior. His current research includes the study of structure and density of silicate liquids at high pressure and melting temperature determinations of silicates and iron alloys at Megbar pressures.

He serves as the manager of the High Pressure Collaborative Access Team (HPCAT) at the Advanced Photon Source (APS). HPCAT operates an APS sector (sector 16) which has four simultaneously operational beamlines dedicated for high pressure research. He also serves as the project manager of the High Pressure Synergetic Consortium (HPSynC) at APS. Guoyin’s experimental activities involve the development and promotion of novel techniques and tools for wide high pressure communities, such as the ultrahigh pressure techniques; laser heated diamond anvil cell work and associated diagnostics; x-ray diffraction, scattering and spectroscopy for structural, electronic and phonon properties; micro-engineering techniques for high pressure sample preparation and characterization.